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Studies with the USF/NASA toxicity screening test method - Exercise wheels and oxygen replenishmentContinuing efforts to improve the University of San Francisco/NASA toxicity screening test method have included the addition of exercise wheels to provide a different measure of incapacitation, and oxygen replenishment to offset any effect of oxygen depletion by the test animals. The addition of exercise wheels limited the number of animals in each test and doubled the required number of tests without any significant improvement in reproducibility. Oxygen replenishment appears to have an effect on survival in the last 5 minutes of the 30-minute test, but the effect is expected to be similar for most materials.
Document ID
19770052816
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
Authors
Hilado, C. J.
(San Francisco Univ. CA, United States)
Cumming, H. J.
(San Francisco, University San Francisco, Calif., United States)
Date Acquired
August 9, 2013
Publication Date
May 1, 1977
Publication Information
Publication: Journal of Combustion Toxicology
Volume: 4
Subject Category
Life Sciences (General)
Accession Number
77A35668
Funding Number(s)
CONTRACT_GRANT: NSG-2039
Distribution Limits
Public
Copyright
Other

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