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Total body water and lean body mass estimated by ethanol dilutionA method for estimating total body water (TBW) using breath analyses of blood ethanol content is described. Regression analysis of ethanol concentration curves permits determination of a theoretical concentration that would have existed if complete equilibration had taken place immediately upon ingestion of the ethanol; the water fraction of normal blood may then be used to calculate TBW. The ethanol dilution method is applied to 35 subjects, and comparison with a tritium dilution method of determining TBW indicates that the correlation between the two procedures is highly significant. Lean body mass and fat fraction were determined by hydrostatic weighing, and these data also prove compatible with results obtained from the ethanol dilution method. In contrast to the radioactive tritium dilution method, the ethanol dilution method can be repeated daily with its applicability ranging from diseased individuals to individuals subjected to thermal stress, strenuous exercise, water immersion, or the weightless conditions of space flights.
Document ID
19770058961
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
Authors
Loeppky, J. A.
(Lovelace Foundation for Medical Education and Research Albuquerque, NM, United States)
Myhre, L. G.
(Lovelace Foundation for Medical Education and Research Albuquerque, NM, United States)
Venters, M. D.
(Lovelace Foundation for Medical Education and Research Albuquerque, NM, United States)
Luft, U. C.
(Lovelace Foundation for Medical Education and Research Albuquerque, N. Mex., United States)
Date Acquired
August 9, 2013
Publication Date
June 1, 1977
Publication Information
Publication: Journal of Applied Physiology: Respiratory
Subject Category
Aerospace Medicine
Accession Number
77A41813
Funding Number(s)
CONTRACT_GRANT: NAS9-14472
Distribution Limits
Public
Copyright
Other

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