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The permuted generator hypothesis for the origin of a genetic codeProtocells had no known means of ensuring that their randomly collected proteins would be duplicated. A possible, albeit inexact, mechanism for protein synthesis in a primitive t-RNA is presented, whereby an oligonucleotide (12 units) in a circular configuration is able to align a generator site with amino acid discriminator sites. In this way, unique anticodons could be specified for each site and replication could occur.
Document ID
19780047474
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
Authors
Folsome, C.
(Hawaii, University Honolulu, Hawaii, United States)
Date Acquired
August 9, 2013
Publication Date
December 1, 1977
Publication Information
Publication: Origin of Life
Volume: 8
Subject Category
Life Sciences (General)
Accession Number
78A31383
Funding Number(s)
CONTRACT_GRANT: NGR-12-001-109
Distribution Limits
Public
Copyright
Other

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