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Effect of ultrasonic irradiation on mammalian cells and chromosomes in vitroHuman peripheral blood and HeLa cells were irradiated in vitro at the ultrasonic frequency of 65 kHz. The whole blood and HeLa cell suspensions were exposed to continuous and pulsed ultrasonic power levels of 0.12, 0.16, 0.72, 1.12 and 2.24 W for a period of one minute. The method of ultrasonic irradiation was carried out with the whole blood or HeLa cell suspensions coupled directly to a cylindrical transducer while heating of the cell suspensions in excess of 41 C was avoided. Irradiated and unirradiated peripheral blood lymphocyte chromosome cultures were prepared and scored for selected numerical and morphological aberrations. There was no significant difference in the frequency of chromosomal aberrations between irradiated and unirradiated cells.
Document ID
19790043226
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
Authors
Roseboro, J. A.
(California Institute of Technology, Jet Propulsion Laboratory, Pasadena Calif., United States)
Buchanan, P.
(North Carolina, University Chapel Hill, N.C., United States)
Norman, A.
(Jet Propulsion Lab., California Inst. of Tech. Pasadena, CA, United States)
Stern, R.
(California, University Los Angeles, Calif., United States)
Date Acquired
August 9, 2013
Publication Date
January 1, 1978
Publication Information
Publication: Physics in Medicine and Biology
Volume: 23
Issue: 2, 19
Subject Category
Life Sciences (General)
Accession Number
79A27239
Distribution Limits
Public
Copyright
Other

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