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Ames interactive molecular model building system - A 3-D computer modelling system applied to the study of the origin of lifeThe investigation of specific interactions among biological molecules must take into consideration the stereochemistry of the structures. Thus, models of the molecules are essential for describing the spatial organization of potentially interacting groups, and estimations of conformation are required for a description of spatial organization. Both the function of visualizing molecules, and that of estimating conformation through calculations of energy, are part of the molecular modeling system described in the present paper. The potential uses of the system in investigating some aspects of the origin of life rest on the assumption that translation of conformation from genetic elements to catalytic elements would have been required for the development of the first replicating systems subject to the process of biological evolution.
Document ID
19790053936
Acquisition Source
Legacy CDMS
Document Type
Conference Proceedings
Authors
Coeckelenbergh, Y.
(NASA Ames Research Center Moffett Field, CA, United States)
Macelroy, R. D.
(NASA Ames Research Center Extraterrestrial Biology Div., Moffett Field, Calif., United States)
Rein, R.
(Roswell Park Memorial Institute Buffalo, N.Y., United States)
Date Acquired
August 9, 2013
Publication Date
January 1, 1978
Subject Category
Chemistry And Materials (General)
Meeting Information
Meeting: Origin of life; Second ISSOL Meeting and Fifth ICOL Meeting
Location: Kyoto
Country: Japan
Start Date: April 5, 1977
End Date: April 10, 1977
Accession Number
79A37949
Distribution Limits
Public
Copyright
Other

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