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The use of Na-22 as a tracer for long-term bone mineral turnover studies.Sodium-22 has been studied as a tracer for bone mineral metabolism in rats and dogs. When incorporated into bone during growth from birth to adulthood, the bone becomes uniformly tagged with Na-22, which is released through the metabolic turnover of the bone. The Na-22 not incorporated in the bone matrix is rapidly excreted within a few days when animals are fed high, but nontoxic levels of NaCl. The Na-22 tracer can be used to measure bone mineral loss in animals during space flight and in research on bone disease.
Document ID
19790063314
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
Authors
Palmer, H. E.
(Battelle Pacific Northwest Labs. Richland, WA, United States)
Rieksts, G. A.
(Battelle Pacific Northwest Labs. Richland, WA, United States)
Palmer, R. F.
(Battelle Pacific Northwest Labs. Richland, WA, United States)
Gillis, M. F.
(Battelle Pacific Northwest Laboratories Richland, Wash., United States)
Date Acquired
August 9, 2013
Publication Date
August 1, 1979
Subject Category
Aerospace Medicine
Accession Number
79A47327
Funding Number(s)
CONTRACT_GRANT: NAS9-14248
CONTRACT_GRANT: NAS9-15544
Distribution Limits
Public
Copyright
Other

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