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Effects of centrifugation stress on pituitary-gonadal function in male ratsThe effects of centrifugation for various lengths of time on circulating levels of luteinizing hormone (LH) and testosterone in male rats were investigated. In a chronic 52-day experiment, centrifugation at 4.1 G significantly reduced LH and testosterone levels for the entire period. Centrifugation at 2.3 G had less effect inasmuch as LH levels were not significantly decreased and testosterone levels were significantly reduced only during the first few days of centrifugation. In more acute experiments, centrifugation at 4.1 G for 4 h resulted in reduced testosterone levels, whereas centrifugation for 15 min did not significantly alter the hormone levels. These results indicate that centrifugation can decrease circulating LH and testosterone levels if the gravitational force is of sufficient magnitude and is maintained for a period of hours. Chronic centrifugation may also inhibit the acute excitatory response of LH to handling and ether stress.
Document ID
19800041817
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
Authors
Gray, G. D.
(Stanford Univ. CA, United States)
Smith, E. R.
(Stanford Univ. CA, United States)
Damassa, D. A.
(Stanford Univ. CA, United States)
Davidson, J. M.
(Stanford University Stanford, Calif., United States)
Date Acquired
August 10, 2013
Publication Date
January 1, 1980
Publication Information
Publication: Journal of Applied Physiology: Respiratory
Subject Category
Life Sciences (General)
Accession Number
80A25987
Funding Number(s)
CONTRACT_GRANT: NAS9-14716
Distribution Limits
Public
Copyright
Other

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