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Experiment K-313: Rat and quail ontogenesisThe potential effects of spaceflight on the processes of mammalian fertilizaton, implantation and embryonic development are investigated. Five female and two male rats were placed together on Day 2 of the flight. By R+17, it was determined that both flight and synchronous females were not carrying normal pregnancies and three of the flight animals were laparotomized. The uterus and ovaries were processed for microscopic analyses. The two remaining flight females were allowed to recover from the exploratory operation, rebred with flight males and delivered normal litters. As a control for potential transplacental effects that might be interpreted as direct spaceflight effects, a series of fertilized Japanese quail (Coturnix japonica) eggs was flown on Cosmos 1129. Although all of the eggs were adversely impacted by an inflight failure of the incubator humidifier on flight Day 13, several embryos were able to progress to a developmental stage equivalent to that of a control 10-12 Day embryo.
Document ID
19810024298
Acquisition Source
Legacy CDMS
Document Type
Other
Authors
Keefe, J. R.
(Bio Space, Inc. Painsville, OH, United States)
Date Acquired
August 11, 2013
Publication Date
August 1, 1981
Publication Information
Publication: NASA. Ames Research Center US Rat Expts. Flown in the Soviet Satellite Cosmos 1129
Subject Category
Life Sciences (General)
Accession Number
81N32841
Distribution Limits
Public
Copyright
Work of the US Gov. Public Use Permitted.

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