NASA Logo

NTRS

NTRS - NASA Technical Reports Server

Back to Results
Formation of the thioester, N,S-diacetylcysteine, from acetaldehyde and N,N'-diacetylcystine in aqueous solution with ultraviolet lightThe thioester, N,S-diacetylcysteine, is formed during the illumination of phosphate buffered (pH 7.0) aqueous solutions of acetaldehyde and N,N'-diacetylcystine with ultraviolet light. The yield of N,S-diacetylcysteine relative to N-acetylcysteine and unidentified products progressively increases as ultraviolet light below 239 nm, 253 nm and 281 nm is cut off with optical filters. When ultraviolet light below 320 nm is removed with an optical filter, there is no detectable reaction. Illumination of 0.025 M N,N'-diacetylcystine with 0.5 M and 1.0 M acetaldehyde with filtered ultraviolet light gives, respectively, 20% and 80% yields of N,S-diacetylcysteine. In the reaction with 1.0 M acetaldehyde, N-acetylcysteine forms early in the reaction and later decreases with its conversion to N,S-diacetylcysteine. The prebiotic significance of these reactions is discussed.
Document ID
19810050514
Document Type
Reprint (Version printed in journal)
External Source(s)
Authors
Weber, A. L.
(Salk Institute of Biological Studies San Diego, Calif., United States)
Date Acquired
August 11, 2013
Publication Date
May 1, 1981
Publication Information
Publication: Journal of Molecular Evolution
Volume: 17
Subject Category
Chemistry And Materials (General)
Accession Number
81A34918
Funding Number(s)
CONTRACT_GRANT: NSG-7627
Distribution Limits
Public
Copyright
Other

Available Downloads

There are no available downloads for this record.
No Preview Available