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Effect of weightlessness on lymphocyte proliferationAn experiment to study the effect of weightlessness on lymphocyte proliferation to detect possible alteration of the cells responsible for the immune response during long-duration space flights is described. Human lymphocytes in culture medium will be delivered shortly before launch in an incubator which will be kept at 37C. Mitogen will be added to the culture. A control without mitogen will be run in parallel. After 70 hours of incubation, radioactive thymidine will be added. After two hours, cellular activity will be stopped by fixation and incubator power switched off. Later, the amount of incorporated thymidine will be determined and the cell morphology and the distribution of cell organelles will be investigated.
Document ID
19820010387
Acquisition Source
Legacy CDMS
Document Type
Other - Other
Authors
Cogoli, A.
(Eidgenoessische Technische Hochschule Zurich, Switzerland)
Date Acquired
August 10, 2013
Publication Date
November 1, 1981
Publication Information
Publication: NASA. Marshall Space Flight Center Spacelab Mission 1 Expt. Descriptions
Subject Category
Aerospace Medicine
Accession Number
82N18261
Distribution Limits
Public
Copyright
Work of the US Gov. Public Use Permitted.
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