Effects of disuse by limb immobilization on different muscle fiber typesThe effects of disuse by limb immobilization on different muscle fiber types are reviewed. It is demonstrated that many changes occurring in atrophying skeletal muscles of young rats can be explained by the duration of the half-lives of muscle proteins. Differences are found to exist in responses of fast- and slow-twitch muscles due to disuse atrophy, and the appearance of plasticity in skeletal muscle begins to occur very soon after changes in the level of contractile activity. Rates of protein degradation increase in slow-twitch muscles at rapidly growing rates after approximately one day of limb immobilization; however, no change in the rates of protein degradation is noted in fast-twitch muscles of young rats.
Document ID
19820033295
Acquisition Source
Legacy CDMS
Document Type
Other - Collected Works
Authors
Booth, F. W. (Texas Univ. Houston, TX, United States)
Seider, M. J. (Texas, University Houston, TX, United States)
Hugman, G. R. (Baylor University Houston, TX, United States)