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Settling of fixed erythrocyte suspension dropletsIt is pointed out that when particles behave collectively rather than individually, the fractionation of micron-size particles on the basis of size, density, and surface characteristics by centrifugation and electrophoresis is hindered. The formation and sedimentation of droplets containing particles represent an extreme example of collective behavior and pose a major problem for these separation methods when large quantities of particles need to be fractionated. Experiments are described that measure droplet sizes and settling rates for a variety of particles and droplets. Expressions relating the particle concentration in a drop to measurable quantities of the fluids and particles are developed. The number of particles in each droplet is then estimated, together with the effective droplet density. Red blood cells from different animals fixed in glutaraldehyde provide model particle groups.
Document ID
Document Type
Reprint (Version printed in journal)
Omenyi, S. N. (NASA Marshall Space Flight Center Huntsville, AL, United States)
Snyder, R. S. (NASA Marshall Space Flight Center Separation Processes Branch, Huntsville, AL, United States)
Date Acquired
August 11, 2013
Publication Date
January 1, 1983
Publication Information
Publication: Biorheology
Volume: 20
Issue: 2, 19
ISSN: 0006-355X
Subject Category
Distribution Limits