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Causes of the triglyceride-lowering effect of exercise training in ratsStudies conducted with human subjects and laboratory animals have consistently shown a reduction in serum triglyceride (TG) in exercise-trained subjects. The obtained data have suggested that this decrease was due to a reduction in hepatic TG secretion. The present investigation, which was conducted with rats trained to attain a high level of spontaneous running activity, provides support for the earlier results. In addition, insights are obtained regarding the mechanism by which exercise lowers TG levels. Since the liver accounts for the vast majority of endogenous very low density lipoprotein (VLDL)-TG secretion, the fall in TG secretion rate seen in exercise-trained (ET) rats must be due to a reduction in hepatic TG secretion.
Document ID
19850032509
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
Authors
Mondon, C. E.
(NASA Ames Research Center Moffett Field, CA, United States)
Dolkas, C. B.
(NASA Ames Research Center Moffett Field, CA, United States)
Tobey, T.
(NASA Ames Research Center Moffett Field, CA, United States)
Reaven, G. M.
(NASA Ames Research Center Moffett Field; Stanford University; U.S. Veterans Administration, Medical Center, Palo Alto, CA, United States)
Date Acquired
August 12, 2013
Publication Date
November 1, 1984
Publication Information
Publication: Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology
Volume: 57
ISSN: 0161-7567
Subject Category
Life Sciences (General)
Accession Number
85A14660
Funding Number(s)
CONTRACT_GRANT: NIH-HL-08506
Distribution Limits
Public
Copyright
Other

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