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Visceral predictors of cardiovascular deconditioning in late middle-aged menA number of visceral and behavioral factors connected with cardiovascular deconditioning were investigated, in order to identify a method for predicting the degree of orthostatic intolerance to spaceflight in several late-middle-aged men (55-65 years). Preliminary measurements were made of: mean arterial blood pressure plasma cortisol levels; and norepinephrine levels. Measurements of core temperature; plasma epinephrine level and subjective arousal from sleep were also obtained. Pairwise correlations were found for each of the variables and the time-to-blackout due centrifugal acceleration of up to +3 Gz. It is shown that the men with relatively low resting blood pressure were at greater risk of developing the clinical signs of cardiovascular deconditioning than were the men with higher basal blood pressure. Some applications of the experimental results to the development of selection criteria for Shuttle crews are discussed.
Document ID
19850044517
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
Authors
Goldwater, D. J.
(NASA Ames Research Center Moffett Field, CA, United States)
De Roshia, C.
(NASA Ames Research Center Moffett Field, CA, United States)
Natelson, B. H.
(U.S. Veterans Administration Medical Center East Orange, NJ, United States)
Levin, B. E.
(New Jersey, College of Medicine and Dentistry, Newark NJ, United States)
Date Acquired
August 12, 2013
Publication Date
March 1, 1985
Publication Information
Publication: Aviation, Space, and Environmental Medicine
Volume: 56
ISSN: 0095-6562
Subject Category
Aerospace Medicine
Accession Number
85A26668
Distribution Limits
Public
Copyright
Other

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