NASA Logo

NTRS

NTRS - NASA Technical Reports Server

Back to Results
Cell Partition in Two Polymer Aqueous PhasesPartition of biological cells in two phase aqueous polymer systems is recognized as a powerful separation technique which is limited by gravity. The synthesis of new, selective polymer ligand conjugates to be used in affinity partition separations is of interest. The two most commonly used polymers in two phase partitioning are dextran and polyethylene glycol. A thorough review of the chemistry of these polymers was begun, particularly in the area of protein attachment. Preliminary studies indicate the importance in affinity partitioning of minimizing gravity induced randomizing forces in the phase separation process. The PEG-protein conjugates that were prepared appear to be ideally suited for achieving high quality purifications in a microgravity environment. An interesting spin-off of this synthetic work was the observation of catalytic activity for certain of our polymer derivatives.
Document ID
19860000672
Acquisition Source
Legacy CDMS
Document Type
Other
Authors
Harris, J. M.
(Alabama Univ. Huntsville, AL, United States)
Date Acquired
August 12, 2013
Publication Date
May 1, 1985
Publication Information
Publication: NASA, Washington Microgravity Sci. and Appl. Program Tasks
Subject Category
Astronautics (General)
Accession Number
86N10139
Funding Number(s)
CONTRACT_GRANT: NAS8-35362
Distribution Limits
Public
Copyright
Work of the US Gov. Public Use Permitted.
Document Inquiry

Available Downloads

There are no available downloads for this record.
No Preview Available