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Testosterone and muscle hypertrophy in female ratsThe effects of chronic treatment with testosterone propionate (TP) on compensatory muscle hypertropy in female rats are examined. The 48 female rats were placed in one of four test groups: (1) no overload (synergist removal), no TP, (2) overload, no TP, (3) no overload + TP, and (4) overload + TP. The technique used to administer the TP is described. The preparation of the plantaris muscle, the analysis of pyruvate oxidation and the determination of malate and lactate dehydrogenases and the noncollogen protein are explained. The results which reveal the effect of overload and TP on body weight, noncollogen protein concentration, lactate and malate dehydrogenase activities, and pyruvate oxidation are presented and discussed. It is concluded that in terms of body weight, protein content, pyruvate, glycolysis, and oxidative metabolisms chronic TP treatments do not change compensatory muscle hypertropy.
Document ID
19860027288
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
Authors
Kuhn, F. E.
(Maryland Univ. Baltimore, MD, United States)
Max, S. R.
(Maryland, University Baltimore, United States)
Date Acquired
August 12, 2013
Publication Date
July 1, 1985
Publication Information
Publication: Journal of Applied Physiology
Volume: 59
ISSN: 0161-7567
Subject Category
Life Sciences (General)
Accession Number
86A12026
Funding Number(s)
CONTRACT_GRANT: NAG2-100
Distribution Limits
Public
Copyright
Other

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