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Record 20 of 726
Regulation of bone mineral loss during lactation
Author and Affiliation:
Brommage, R.(Wisconsin Univ., Madison, WI, United States)
Deluca, H. F.(Wisconsin, University, Madison, United States)
Abstract: The effects of varyng dietary calcium and phosphorous levels, vitamin D deficiency, oophorectomy, adrenalectomy, and simultaneous pregnancy on bone mineral loss during lactation in rats are studied. The experimental procedures and evaluations are described. The femur ash weight of lactating and nonlactating rats are calculated. The data reveals that a decrease in dietary calcium of 0.02 percent results in an increased loss of bone mineral, an increase in calcium to 1.4 percent does not lessen bone mineral loss, and bone mineral loss in vitamin D deficient rats is independent of calcium levels. It is observed that changes in dietary phosphorous level, oophorectomy, adrenalectomy, and simultaneous pragnancy do not reduce bone mineral loss during lactation. The analysis of various hormones to determine the mechanism that triggers bone mineral loss during lactation is presented.
Publication Date: Jan 01, 1985
Document ID:
19860037975
(Acquired Nov 28, 1995)
Accession Number: 86A22713
Subject Category: LIFE SCIENCES (GENERAL)
Document Type: Journal Article
Publication Information: American Journal of Physiology: Endocrinology and Metabolism (ISSN 0193-1849); 248; E182-E18
Publisher Information: United States
Contract/Grant/Task Num: NIH-AM-14881; NAG2-167
Financial Sponsor: NASA; United States
Organization Source: Wisconsin Univ.; Madison, WI, United States
Description: 6p; In English
Distribution Limits: Unclassified; Publicly available; Unlimited
Rights: Copyright
NASA Terms: BONE DEMINERALIZATION; CALCIFEROL; CALCIUM METABOLISM; PHOSPHORUS METABOLISM; PREGNANCY; REGULATORY MECHANISMS (BIOLOGY); RATS
Imprint And Other Notes: American Journal of Physiology: Endocrinology and Metabolism (ISSN 0193-1849), vol. 248, 1985, p. E182-E187. Research supported by the Wisconsin Alumni Research Foundation.
Miscellaneous Notes: Research supported by the Wisconsin Alumni Research Foundation
Availability Source: Other Sources
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