NASA Logo

NTRS

NTRS - NASA Technical Reports Server

Back to Results
Morphology of human embryonic kidney cells in culture after space flightThe ability of human embyronic kidney cells to differentiate into small epithelioid, large epithelioid, domed, and fenestrated morphological cell types following space flight is examined. Kidney cells exposed to 1 day at 1 g, then 1 day in orbit, and a 12 minute passage through the electrophoretic separator are compared with control cultures. The data reveal that 70 percent of small epithelioid, 16 percent of large epithelioid, 9 percent of dome-forming, and 5 percent of fenestrated cells formed in the space exposed cells; the distributions correlate well with control data. The formation of domed cells from cells cultured from low electrophoretic mobility fractions and small epithelioid cells from high mobility fractions is unaffected by space flight conditions. It is concluded that storage under microgravity conditions does not influence the morphological differentiation of human embryonic kidney cells in low-passage culture.
Document ID
19860045714
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
Authors
Todd, P.
(NASA Lyndon B. Johnson Space Center Houston, TX, United States)
Kunze, M. E.
(NASA Lyndon B. Johnson Space Center Houston, TX, United States)
Williams, K.
(NASA Lyndon B. Johnson Space Center Houston, TX, United States)
Morrison, D. R.
(NASA Lyndon B. Johnson Space Center Houston, TX, United States)
Lewis, M. L.
(NASA Lyndon B. Johnson Space Center Houston, TX, United States)
Barlow, G. H.
(NASA Johnson Space Center Houston, TX; Bioprocessing and Pharmaceutical Research Center, Philadelphia; Pennsylvania State Univ, United States)
Date Acquired
August 12, 2013
Publication Date
December 1, 1985
Publication Information
Publication: Physiologist, Supplement
Volume: 28
ISSN: 0031-9376
Subject Category
Life Sciences (General)
Accession Number
86A30452
Distribution Limits
Public
Copyright
Other

Available Downloads

There are no available downloads for this record.
No Preview Available