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Muscle protein and glycogen responses to recovery from hypogravity and unloading by tail-cast suspensionPrevious studies in this laboratory using the tail-bast hindlimb suspension model have shown that there are specific changes in protein and carbohydrate metabolism in the soleus muscle due to unloading. For example, 6 days of unloading caused a 27 percent decrease in mass and a 60 percent increse in glycogen content in the soleus muscle, while the extensor digitorum longus muscle was unaffected. Also, fresh tissue tyrosine and its in vitro release from the muscle are increased in the unloaded soleus, indicating that this condition causes a more negative protein balance. With these results in mind, studies to investigate the effect of hypogravity on protein and carbohydrate metabolism in a number of rat hindlimb muscles were carried out.
Document ID
19860045719
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
Authors
Henriksen, E. J.
(Arizona Univ. Tucson, AZ, United States)
Tischler, M. E.
(Arizona Univ. Tucson, AZ, United States)
Jacob, S.
(Arizona Univ. Tucson, AZ, United States)
Cook, P. H.
(Arizona, University Tucson, United States)
Date Acquired
August 12, 2013
Publication Date
December 1, 1985
Publication Information
Publication: Physiologist, Supplement
Volume: 28
ISSN: 0031-9376
Subject Category
Life Sciences (General)
Accession Number
86A30457
Funding Number(s)
CONTRACT_GRANT: NAGW-227
Distribution Limits
Public
Copyright
Other

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