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Reduction of the spermatogonial population in rat testes flown on Space Lab-3Quantization of the testicular spermatogonial population reduction in six rats is performed 12 hours after their return from seven days aboard Space Lab-3. The observed 7.1 percent organ weight loss, and 7.5 percent stage six spermatogonial cell population reduction in comparison with control rats correlate very well. Accurate dosimetry was not conducted on board, but radiation can not be considered the primary cause of the observed change. The decrease in protein kinase in the heart of these rats indicates that stress from adapting to weightlessness, the final jet flight, or other sources, is an important factor.
Document ID
19860045728
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
Authors
Philpott, D. E.
(NASA Ames Research Center Moffett Field, CA, United States)
Stevenson, J.
(NASA Ames Research Center Moffett Field, CA, United States)
Corbett, R.
(NASA Ames Research Center Moffett Field, CA, United States)
Sapp, W.
(NASA Ames Research Center Moffett Field, CA, United States)
Williams, C.
(Tuskegee Institute AL, United States)
Date Acquired
August 12, 2013
Publication Date
December 1, 1985
Publication Information
Publication: Physiologist, Supplement
Volume: 28
ISSN: 0031-9376
Subject Category
Life Sciences (General)
Accession Number
86A30466
Distribution Limits
Public
Copyright
Other

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