NTRS - NASA Technical Reports Server
Protein crystal growth in spaceThe advantages of protein crystallization in space, and the applications of protein crystallography to drug design, protein engineering, and the design of synthetic vaccines are examined. The steps involved in using protein crystallography to determine the three-dimensional structure of a protein are discussed. The growth chamber design and the hand-held apparatus developed for protein crystal growth by vapor diffusion techniques (hanging-drop method) are described; the experimental data from the four Shuttle missions are utilized to develop hardware for protein crystal growth in space and to evaluate the effects of gravity on protein crystal growth.
Bugg, C. E. (Alabama, University Birmingham, United States) Clifford, D. W. (McDonnell Douglas Astronautics Co. Saint Louis, MO, United States)
August 13, 2013
January 1, 1987