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Femur-bending properties as influenced by gravity. V - Strength vs. calcium and gravity in rats exposed for 2 weeksThe dependence of gravitationally related changes in femur bone strength on the comparable changes in calcium content was investigated in rats exposed to chronic simulations of altered gravity from the 28th to 42nd day of age. Zero G was simulated by harness suspension and 3 G by centrifugation. Bone strength (S) was determined by bending (using modified quasi-static cantilever bending methods and equipment described by Wunder et al., 1977 and 1979) and Ca content (C, by mass pct) determined by atomic absorption spectrometry; results were compared with data obtained on both normal and harnessed control animals at 1 G. Multiple regression showed significant dependence of S upon earth's gravity, independent from C, for which there was no significant coefficient of partial regression. It is suggested that the lack of S/C correlation might have been due to the fact that considerable fraction of the calcium in these young, developing bones has not yet crystallized into the hydroxyapatite which provides strength.
Document ID
Document Type
Reprint (Version printed in journal)
Wunder, Charles C.
(Iowa Univ. Iowa City, IA, United States)
Cook, Kenneth M.
(Iowa Univ. Iowa City, IA, United States)
Watkins, Stanley R.
(Iowa Univ. Iowa City, IA, United States)
Moressi, William J.
(Iowa, University Iowa City; Coe College, Cedar Rapids, IA; Winthrop College, Rock Hills, SC, United States)
Date Acquired
August 13, 2013
Publication Date
October 1, 1987
Publication Information
Publication: Aviation, Space, and Environmental Medicine
Volume: 58
ISSN: 0095-6562
Subject Category
Life Sciences (General)
Accession Number
Funding Number(s)
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