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Effect of anabolic steroids on skeletal muscle mass during hindlimb suspensionThe effect of treatment with an anabolic steroid (nandrolone decanoate) on the muscle mass of plantaris and soleus of a rats in hindlimb suspension, and on the isomyosin expression in these muscles, was investigated in young female rats divided into four groups: normal control (NC), normal steroid (NS), normal suspension (N-sus), and suspension steroid (sus-S). Steroid treatment of suspended animals (sus-S vs N-sus) was found to partially spare body weight and muscle weight, as well as myofibril content of plantaris (but not soleus), but did not modify the isomyosin pattern induced by suspension. In normal rats (NS vs NC), steroid treatment did enhance body weight and plantaris muscle weight; the treatment did not alter isomyosin expression in either muscle type.
Document ID
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
Tsika, R. W.
(California Univ. Irvine, CA, United States)
Herrick, R. E.
(California Univ. Irvine, CA, United States)
Baldwin, K. M.
(California, University Irvine, United States)
Date Acquired
August 13, 2013
Publication Date
November 1, 1987
Publication Information
Publication: Journal of Applied Physiology
Volume: 63
ISSN: 0161-7567
Subject Category
Life Sciences (General)
Accession Number
Funding Number(s)
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