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evaporation kinetics in the hanging drop method of protein crystal growthAn engineering analysis of the rate of evaporation of solvent in the hanging drop method of protein crystal growth is presented; these results are applied to 18 different drop and well arrangements commonly encountered in the laboratory, taking into account the chemical nature of the salt, the drop size and shape, the drop concentration, the well size, the well concentration, and the temperature. It is found that the rate of evaporation increases with temperature, drop size, and with the salt concentration difference between the drop and the well. The evaporation possesses no unique half-life. Once the salt in the drop achieves about 80 percent of its final concentration, further evaporation suffers from the law of diminishing returns.
Document ID
19880041348
Document Type
Conference Paper
Authors
Baird, James K.
(Alabama Univ. Huntsville, AL, United States)
Frieden, Richard W.
(Alabama Univ. Huntsville, AL, United States)
Meehan, E. J., Jr.
(Alabama Univ. Huntsville, AL, United States)
Twigg, Pamela J.
(Alabama Univ. Huntsville, AL, United States)
Howard, Sandra B.
(Alabama, University Huntsville, United States)
Fowlis, William A.
(NASA Marshall Space Flight Center Huntsville, AL, United States)
Date Acquired
August 13, 2013
Publication Date
January 1, 1987
Subject Category
MATERIALS PROCESSING
Meeting Information
Materials processing in the reduced gravity environment of space(Boston, MA)
Funding Number(s)
CONTRACT_GRANT: NAS8-36611
Distribution Limits
Public
Copyright
Other