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Microencapsulation Of Living CellsIn experimental technique, living cells and other biological materials encapsulated within submillimeter-diameter liquid-filled spheres. Sphere material biocompatible, tough, and compliant. Semipermeable, permitting relatively small molecules to move into and out of sphere core but preventing passage of large molecules. New technique promises to make such spherical capsules at high rates and in uniform, controllable sizes. Capsules injected into patient through ordinary hypodermic needle. Promising application for technique in treatment of diabetes. Also used to encapsulate pituitary cells and thyroid hormone adrenocortical cells for treatment of other hormonal disorders, to encapsulate other secreting cells for transplantation, and to package variety of pharmaceutical products and agricultural chemicals for controlled release.
Document ID
19890000588
Acquisition Source
Legacy CDMS
Document Type
Other - NASA Tech Brief
Authors
Chang, Manchium
(Caltech)
Kendall, James M.
(Caltech)
Wang, Taylor G.
(Caltech)
Date Acquired
August 14, 2013
Publication Date
November 1, 1989
Publication Information
Publication: NASA Tech Briefs
Volume: 13
Issue: 11
ISSN: 0145-319X
Subject Category
Life Sciences
Report/Patent Number
NPO-17434
Accession Number
89B10588
Distribution Limits
Public
Copyright
Work of the US Gov. Public Use Permitted.

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