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Clenbuterol, a beta(2)-agonist, retards atrophy in denervated musclesThe effects of a beta(2) agonist, clenbuterol, on the protein content as well as on the contractile strength and the muscle fiber cross-sectional area of various denervated muscles from rats were investigated. It was found that denervated soleus, anterior tibialis, and gastrocnemius muscles, but not the extensor digitorum longus, of rats treated for 2-3 weeks with clenbuterol contained 95-110 percent more protein than denervated controls. The twofold difference in the protein content of denervated solei was paralleled by similar changes in contractile strength and muscle fiber cross-sectional area.
Document ID
19890032458
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
Authors
Zeman, Richard J.
(State Univ. of New York Brooklyn, NY, United States)
Ludemann, Robert
(State Univ. of New York Brooklyn, NY, United States)
Etlinger, Joseph D.
(New York, State University Brooklyn, United States)
Date Acquired
August 14, 2013
Publication Date
January 1, 1987
Publication Information
Publication: American Journal of Physiology: Endocrinology and Metabolism
ISSN: 0193-1849
Subject Category
Life Sciences (General)
Accession Number
89A19829
Funding Number(s)
CONTRACT_GRANT: NIH-HL-31494
CONTRACT_GRANT: NAG2-162
Distribution Limits
Public
Copyright
Other

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