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Fluid/electrolyte and endocrine changes in space flightThe primary effects of space flight that influence the endocrine system and fluid and electrolyte regulation are the reduction of hydrostatic gradients, reduction in use and gravitational loading of bone and muscle, and stress. Each of these sets into motion a series of responses that culminates in alteration of some homeostatic set points for the environment of space. Set point alterations are believed to include decreases in venous pressure; red blood cell mass; total body water; plasma volume; and serum sodium, chloride, potassium, and osmolality. Serum calcium and phosphate increase. Hormones such as erythropoietin, atrial natriuretic peptide, aldosterone, cortisol, antidiuretic hormone, and growth hormone are involved in the dynamic processes that bring about the new set points. The inappropriateness of microgravity set points for 1-G conditions contributes to astronaut postflight responses.
Document ID
19890044941
Acquisition Source
Legacy CDMS
Document Type
Conference Paper
Authors
Huntoon, Carolyn Leach
(NASA Johnson Space Center Houston, TX, United States)
Date Acquired
August 14, 2013
Publication Date
January 1, 1989
Subject Category
Aerospace Medicine
Accession Number
89A32312
Distribution Limits
Public
Copyright
Other

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