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Some acyclic analogues of nucleotides and their template-directed reactionsBismonophosphoimidazolides of acyclic analogues of guanosine IV and adenosine V were synthesized. They undergo oligomerization in the presence of complementary polynucleotide templates. Details of their synthesis and their subsequent template- and nontemplate-directed reactions are described, and their possible relevance to the origin of life is discussed.
Document ID
19890057863
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
Authors
Tohidi, Mahrokh (Salk Inst. for Biological Studies San Diego, CA, United States)
Orgel, Leslie E. (Salk Institute for Biological Studies San Diego, CA, United States)
Date Acquired
August 14, 2013
Publication Date
January 1, 1989
Publication Information
Publication: Journal of Molecular Evolution
Volume: 28
ISSN: 0022-2844
Subject Category
Chemistry And Materials (General)
Accession Number
89A45234
Funding Number(s)
CONTRACT_GRANT: NGR-05-067-001
Distribution Limits
Public
Copyright
Other

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