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Hollow-Fiber ClinostatHollow-fiber clinostat, is bioreactor used to study growth and other behavior of cells in simulated microgravity. Cells under study contained in porous hollow fiber immersed in culture medium inside vessel. Bores in hollow fiber allow exchange of gases, nutrients, and metabolic waste products between living cells and external culture media. Hollow fiber lies on axis of vessel, rotated by motor equipped with torque and speed controls. Desired temperature maintained by operating clinostat in standard tissue-culture incubator. Axis of rotation made horizontal or vertical. Designed for use with conventional methods of sterilization and sanitation to prevent contamination of specimen. Also designed for asepsis in assembly, injection of specimen, and exchange of medium.
Document ID
19900000311
Acquisition Source
Legacy CDMS
Document Type
Other - NASA Tech Brief
Authors
Rhodes, Percy H.
(NASA Marshall Space Flight Center, Huntsville, AL.)
Miller, Teresa Y.
(NASA Marshall Space Flight Center, Huntsville, AL.)
Snyder, Robert S.
(NASA Marshall Space Flight Center, Huntsville, AL.)
Date Acquired
August 14, 2013
Publication Date
June 1, 1990
Publication Information
Publication: NASA Tech Briefs
Volume: 14
Issue: 6
ISSN: 0145-319X
Subject Category
Life Sciences
Report/Patent Number
MFS-28370
Accession Number
90B10311
Distribution Limits
Public
Copyright
Work of the US Gov. Public Use Permitted.

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