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Thin film bioreactors in spaceStudies from the Skylab, SL-3 and D-1 missions have demonstrated that biological organisms grown in microgravity have changes in basic cellular functions such as DNA, mRNA and protein synthesis, cytoskeleton synthesis, glucose utilization, and cellular differentiation. Since microgravity could affect prokaryotic and eukaryotic cells at a subcellular and molecular level, space offers an opportunity to learn more about basic biological systems with one inmportant variable removed. The thin film bioreactor will facilitate the handling of fluids in microgravity, under constant temperature and will allow multiple samples of cells to be grown with variable conditions. Studies on cell cultures grown in microgravity would make it possible to identify and quantify changes in basic biological function in microgravity which are needed to develop new applications of orbital research and future biotechnology.
Document ID
19900028013
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
Authors
Hughes-Fulford, M.
(NASA Johnson Space Center Houston, TX; USVA, Medical Center; California, University, San Francisco, CA, United States)
Scheld, H. W.
(Phyto Resource Research, Inc. College Station, TX, United States)
Date Acquired
August 14, 2013
Publication Date
January 1, 1989
Publication Information
Publication: - Gravitational Biology, Espoo, Finland, July 18-29, 1988) Advances in Space Research
ISSN: 0273-1177
Subject Category
Life Sciences (General)
Accession Number
90A15068
Distribution Limits
Public
Copyright
Other

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