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Effect of a central redistribution of fluid volume on response to lower-body negative pressureCardiovascular responses to lower-body negative pressure (LBNP) were studied following 1 hour of 6-deg head-down tilt to determine whether a redistribution of blood volume toward the central circulation modifies the subsequent response to orthostatic stress. Responses of 12 men, ages 30-39 years, were evaluated by electrocardiography, impedance cardiography, sphygmomanometry, and measurement of calf circumference. During the LBNP that followed head-down tilt, as compared with control LBNP (no preceding head-down tilt) subjects, had smaller stroke volume and cardiac output, greater total peripheral resistance, and less calf enlargement. These differences reflect differences in the variables immediately preceding LBNP. Magnitudes of the responses from pre-LBNP to each pressure stage of the LBNP procedure did not differ between protocols. Mean and diastolic arterial pressures were slightly elevated after LBNP-control, but they fell slightly during LBNP post-tilt.
Document ID
19900033090
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
Authors
Tomaselli, Clare M.
(NASA John F. Kennedy Space Center Cocoa Beach, FL, United States)
Frey, Mary A. B.
(NASA John F. Kennedy Space Center Cocoa Beach, FL, United States)
Kenney, Richard A.
(NASA John F. Kennedy Space Center Cocoa Beach, FL, United States)
Hoffler, G. Wyckliffe
(NASA Kennedy Space Center; Bionetics Corp., Cocoa Beach, FL; George Washington University Washington, DC, United States)
Date Acquired
August 14, 2013
Publication Date
January 1, 1990
Publication Information
Publication: Aviation, Space, and Environmental Medicine
Volume: 61
ISSN: 0095-6562
Subject Category
Aerospace Medicine
Accession Number
90A20145
Distribution Limits
Public
Copyright
Other

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