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Influence of 7 days of hindlimb suspension and intermittent weight support on rat muscle mechanical propertiesThe effect of intermittent periods of weight support on a decrease in mass of the soleus (Sol) and medial gastrocnemius (MG) muscles atrophied by hindlimb suspension (HS) was investigated in rats subjected to continuous HS for seven days or an HS plus intermittent (10 min every 6 hrs of slow walking on a treadmill) weight support (HS-WS). After 7 d HS, the Sol weight relative to body weight was 21 and 9 percent lower in Hs and HS-WS, respectively, than in control rats. Maximum tetanic tension/muscle mass ratio was significantly lower in HS than in controls; the HS-WS rats had values similar to controls, whereas the maximum tetanic tension/muscle weight was significantly elevated in HS-WS compared to controls. Contraction times were 25 percent faster in the Sol and unchanged in the MG of HS rats, indicating that a low-force short-duration exercise regime results in a significant functional recovery in the 'slow' Sol, whereas the 'fast' MG is less affected.
Document ID
19900038955
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
Authors
Pierotti, David J.
(California Univ. Los Angeles, CA, United States)
Roy, Roland R.
(California Univ. Los Angeles, CA, United States)
Flores, Vinicio
(California Univ. Los Angeles, CA, United States)
Edgerton, Reggie
(California, University Los Angeles, United States)
Date Acquired
August 14, 2013
Publication Date
March 1, 1990
Publication Information
Publication: Aviation, Space, and Environmental Medicine
Volume: 61
ISSN: 0095-6562
Subject Category
Life Sciences (General)
Accession Number
90A26010
Funding Number(s)
CONTRACT_GRANT: NIH-NS-16333
CONTRACT_GRANT: NCA2-IR-390-502
Distribution Limits
Public
Copyright
Other

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