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Cosmos 1887 mission overview - Effects of microgravity on rat body and adrenal weights and plasma constituentsTissues of male, specific pathogen-free Wistar rats flown on the Cosmos 1887 biosatellite are studied. First the mission is described, and then analytical methods are outlined. It is noted that flight rats grew more slowly and had larger adrenal glands than earth gravity controls. Analysis of plasma reveals increased concentrations of hepatic alkaline phosphatase, glucose, urea nitrogen, and creatinine in flight rats. In contrast, electrolytes, total protein, albumin, corticosteron, prolactin, and immunoreactive growth hormone levels are unchanged. However, testosterone concentration is marginally decreased after flight and thyroid hormone levels are suggestive of reduced thyroid function.
Document ID
19900046958
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
Authors
Grindeland, R. E.
(NASA Ames Research Center Moffett Field, CA, United States)
Vasques, M.
(NASA Ames Research Center Moffett Field, CA, United States)
Arnaud, S. B.
(NASA Ames Research Center Moffett Field, CA, United States)
Popova, I. A.
(Institut Mediko-Biologicheskikh Problem Moscow, Ussr)
Date Acquired
August 14, 2013
Publication Date
January 1, 1990
Publication Information
Publication: FASEB Journal
Volume: 4
ISSN: 0892-6638
Subject Category
Life Sciences (General)
Accession Number
90A34013
Distribution Limits
Public
Copyright
Other

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