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Prevention of space flight induced soft tissue calcification and disuse osteoporosisMedical complications such as renal stone formation, increased uric acid output, and disuse osteoporosis are discussed. A series of experiments was conducted in order to study and eventually reduce these flight hazards. Attempts to prevent the negative calcium balance and loss of calcaneal density during prolonged bed rest had only a limited success. Of the five biochemical regiments tested, only diphosphonate applied in a high dose had a positive effect in elliminating mineral losses. It is found that clodronate can prevent disuse osteoporosis and that fluoride can enhance bone formation. It is concluded that exercises, combined with pharmaceutical agents, are beneficial during long-duration space missions.
Document ID
19910029540
Acquisition Source
Legacy CDMS
Document Type
Conference Paper
Authors
Schneider, Victor S.
(Texas, University Houston, United States)
Leblanc, Adrian
(Baylor College of Medicine Houston, TX, United States)
Huntoon, Carolyn L.
(NASA Johnson Space Center Houston, TX, United States)
Date Acquired
August 14, 2013
Publication Date
October 1, 1990
Subject Category
Aerospace Medicine
Report/Patent Number
IAF PAPER 90-512
Accession Number
91A14163
Distribution Limits
Public
Copyright
Other

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