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Polyethylene Glycol PropionaldehydesNew class of compounds derived from polyethylene glycol (PEG's) namely, PEG-propionaldehydes, offers two important advantages over other classes of PEG aldehyde derivatives: compounds exhibit selective chemical reactivity toward amino groups and are stable in aqueous environment. PEG's and derivatives used to couple variety of other molecules, such as, to tether protein molecules to surfaces. Biotechnical and biomedical applications include partitioning of two phases in aqueous media; immobilization of such proteins as enzymes, antibodies, and antigens; modification of drugs; and preparation of protein-rejecting surfaces. In addition, surfaces coated with PEG's and derivatives used to control wetting and electroosmosis. Another potential application, coupling to aminated surfaces.
Document ID
19920000162
Acquisition Source
Legacy CDMS
Document Type
Other - NASA Tech Brief
Authors
Harris, Joe M.
(Alabama Univ.)
Sedaghat-Herati, Mohammad R.
(Alabama Univ.)
Karr, Laurel J.
(NASA Marshall Space Flight Center, Huntsville, AL.)
Date Acquired
August 15, 2013
Publication Date
March 1, 1992
Publication Information
Publication: NASA Tech Briefs
Volume: 16
Issue: 3
ISSN: 0145-319X
Subject Category
Materials
Report/Patent Number
MFS-26127
Accession Number
92B10162
Distribution Limits
Public
Copyright
Work of the US Gov. Public Use Permitted.

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