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Dynamic cell culture system (7-IML-1)This experiment is one of the Biorack experiments being flown on the International Microgravity Laboratory 1 (MIL-1) mission as part of an investigation studying cell proliferation and performance in space. One of the objectives of this investigation is to assess the potential benefits of bioprocessing in space with the ultimate goal of developing a bioreactor for continuous cell cultures in space. This experiment will test the operation of an automated culture chamber that was designed for use in a Bioreactor in space. The device to be tested is called the Dynamic Cell Culture System (DCCS). It is a simple device in which media are renewed or chemicals are injected automatically, by means of osmotic pumps. This experiment uses four Type I/O experiment containers. One DCCS unit, which contains a culture chamber with renewal of medium and a second chamber without a medium supply fits in each container. Two DCCS units are maintained under zero gravity conditions during the on-orbit period. The other two units are maintained under 1 gh conditions in a 1 g centrifuge. The schedule for incubator transfer is given.
Document ID
19920014372
Document Type
Other
Authors
Cogoli, Augusto (Eidgenoessische Technische Hochschule Zurich, Switzerland)
Date Acquired
September 6, 2013
Publication Date
February 1, 1992
Publication Information
Publication: NASA. Marshall Space Flight Center, First International Microgravity Laboratory Experiment Descriptions
Subject Category
LIFE SCIENCES (GENERAL)
Distribution Limits
Public
Copyright
Work of the US Gov. Public Use Permitted.