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Record Details

Record 70 of 5218
Ventral horn cell responses to spaceflight and hindlimb suspension
Author and Affiliation:
Jiang, Bian(NASA Ames Research Center, Moffett Field, CA, United States)
Roy, Roland R.(NASA Ames Research Center, Moffett Field, CA, United States)
Poliakov, I. V.(NASA Ames Research Center, Moffett Field, CA, United States)
Krasnov, I. B.(NASA Ames Research Center, Moffett Field, CA, United States)
Edgerton, V. R.(California, University, Los Angeles)
Abstract: Ventral horn cells of the lumbosacral enlargement of the spinal cord were studied focusing on the succinate dehydrogenase (SDH) activity and cross-sectional area of the soma of ventral horn cells which were measured using a computer-aided image-processing system. The relationships between the soma size and SDH activities of lumber ventral horn cells after 14 days of spaceflight (Cosmos 2044) or of hindlimb suspension are considered. Three groups of rats under consideration include control, 14-day spaceflight, and 14-day hindlimb suspension. Data obtained indicate that, compared to the control group, the population distribution of SDH activities in the flight rats shifted toward higher activities, whereas in the suspended rats the distribution shifted toward lower activities. The interactive effects within individual cells showed that there was a higher percentage of small cells with high SDH activities in the flight than in the control or suspended rats. It is suggested that changes in ventral horn cells were due to factors other than simply the absence of weight support.
Publication Date: Aug 01, 1992
Document ID:
19920068862
(Acquired Nov 22, 1995)
Accession Number: 92A51486
Subject Category: LIFE SCIENCES (GENERAL)
Document Type: Journal Article
Publication Information: Journal of Applied Physiology, Supplement (ISSN 8750-7587); 73; 2, Au
Publisher Information: United States
Contract/Grant/Task Num: NCC2-535
Financial Sponsor: NASA; United States
Organization Source: NASA Ames Research Center; Moffett Field, CA, United States
Description: 5p; In English
Distribution Limits: Unclassified; Publicly available; Unlimited
Rights: Copyright
NASA Terms: BIOASTRONAUTICS; CELLS (BIOLOGY); LIMBS (ANATOMY); SPACE FLIGHT; SPACEBORNE EXPERIMENTS; SPINAL CORD; COMPUTER AIDED TOMOGRAPHY; COSMOS SATELLITES; DISTRIBUTION FUNCTIONS; IMAGE PROCESSING; SUSPENDING (HANGING); TISSUES (BIOLOGY); WEIGHTLESSNESS
Imprint And Other Notes: Journal of Applied Physiology, Supplement (ISSN 8750-7587), vol. 73, no. 2, Aug. 1992, p. 107S-111S.
Availability Source: Other Sources
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