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Effects of microgravity or simulated launch on testicular function in ratsReproductive toxicology and cellular and molecular biology approaches were used to evaluate testicular function in rats from Cosmos 2044. It is found that concentrations of testosterone in testicular tissue or peripheral blood plasma were reduced in flight rates to less than 20 percent of values for simulated-launch or vivarium controls. Spermatogenesis was essentially normal in flight rats, but production of testosterone was severely depressed.
Document ID
19920068873
Document Type
Reprint (Version printed in journal)
Authors
Amann, R. P.
(NASA Ames Research Center Moffett Field, CA, United States)
Deaver, D. R.
(NASA Ames Research Center Moffett Field, CA, United States)
Zirkin, B. R.
(NASA Ames Research Center Moffett Field, CA, United States)
Grills, G. S.
(NASA Ames Research Center Moffett Field, CA, United States)
Sapp, W. J.
(NASA Ames Research Center Moffett Field, CA, United States)
Veeramachaneni, D. N. R.
(NASA Ames Research Center Moffett Field, CA, United States)
Clemens, J. W.
(NASA Ames Research Center Moffett Field, CA, United States)
Banerjee, S. D.
(NASA Ames Research Center Moffett Field, CA, United States)
Folmer, J.
(NASA Ames Research Center Moffett Field, CA, United States)
Gruppi, C. M.
(Colorado State University Fort Collins; Pennsylvania State University, University Park; Johns Hopkins University, Baltimore, M, United States)
Date Acquired
August 15, 2013
Publication Date
August 1, 1992
Publication Information
Publication: Journal of Applied Physiology, Supplement
Volume: 73
Issue: 2 Au
ISSN: 8750-7587
Subject Category
Life Sciences (General)
Accession Number
92A51497
Funding Number(s)
CONTRACT_GRANT: NIH-G12-RR-03059-01A1
CONTRACT_GRANT: NCC2-455
CONTRACT_GRANT: NIH-HD-07313
CONTRACT_GRANT: NAG2-613
CONTRACT_GRANT: NAGW-1579
CONTRACT_GRANT: NAG2-597
CONTRACT_GRANT: NCC2-12
CONTRACT_GRANT: NAG2-612
Distribution Limits
Public
Copyright
Other

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