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Fluorescent-Antibody Measurement Of Cancer-Cell UrokinaseCombination of laboratory techniques provides measurements of amounts of urokinase in and between normal and cancer cells. Includes use of fluorescent antibodies specific against different forms of urokinase-type plasminogen activator, (uPA), fluorescence microscopy, quantitative analysis of images of sections of tumor tissue, and flow cytometry of different uPA's and deoxyribonucleic acid (DNA) found in suspended-tumor-cell preparations. Measurements provide statistical method for indicating or predicting metastatic potentials of some invasive tumors. Assessments of metastatic potentials based on such measurements used in determining appropriate follow-up procedures after surgical removal of tumors.
Document ID
19930000801
Acquisition Source
Legacy CDMS
Document Type
Other - NASA Tech Brief
Authors
Morrison, Dennis R.
(NASA Lyndon B. Johnson Space Center, Houston, TX.)
Date Acquired
August 16, 2013
Publication Date
December 1, 1993
Publication Information
Publication: NASA Tech Briefs
Volume: 17
Issue: 12
ISSN: 0145-319X
Subject Category
Life Sciences
Report/Patent Number
MSC-21715
Accession Number
93B10801
Distribution Limits
Public
Copyright
Work of the US Gov. Public Use Permitted.

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