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Effects of running the Bostom Marathon on plasma concentrations of large neutral amino acidsPlasma large neutral amino acid concentrations were measured in thirty-seven subjects before and after completing the Boston Marathon. Concentrations of tyrosine, phenylalanine, and methionine increased, as did their 'plasma ratios' (i.e., the ratio of each amino acid's concentration to the summed plasma concentrations of the other large neutral amino acids which compete with it for brain uptake). No changes were noted in the plasma concentrations of tryptophan, leucine, isoleucine, nor valine; however, the 'plasma ratios' of valine, leucine, and isoleucine all decreased. These changes in plasma amino acid patterns may influence neurotransmitter synthesis.
Document ID
19930043051
Document Type
Reprint (Version printed in journal)
External Source(s)
Authors
Conlay, L. A. (NASA Headquarters Washington, DC United States)
Wurtman, R. J. (NASA Headquarters Washington, DC United States)
Lopez G-Coviella, I. (NASA Headquarters Washington, DC United States)
Blusztajn, J. K. (NASA Headquarters Washington, DC United States)
Vacanti, C. A. (NASA Headquarters Washington, DC United States)
Logue, M. (NASA Headquarters Washington, DC United States)
During, M. (NASA Headquarters Washington, DC United States)
Caballero, B. (NASA Headquarters Washington, DC United States)
Maher, T. J. (NASA Headquarters Washington, DC United States)
Evoniuk, G. (MIT, Cambridge; Massachusetts General Hospital; Harvard Univ. Boston, United States)
Date Acquired
August 16, 2013
Publication Date
January 1, 1989
Publication Information
Publication: Journal of Neural Transmission
ISSN: 0300-9564
Subject Category
AEROSPACE MEDICINE
Distribution Limits
Public
Copyright
Other