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Human performance and physiological function during a 24-hr exposure to 1 percent bromotrifluoromethane (Halon 1301)Performance and physiological measurements were obtained from four pairs of men exposed for 24 hr to 1 percent (10,000 ppm) Halon 1301 (CBrF3) and to air with order counterbalanced using a double-blind protocol. Cognitive and motor performance was assessed before, during, and after the exposures, using seven scales of the Automated Portable Testing System, which produced 13 measures of performance. Halon inhalation induced decrements in 2 of the 13 measures, but actual and estimated magnitudes of the decrements were no greater than 5 percent of baseline values. Physiological data obtained before, during, and after the exposures revealed significant changes during Halon inhalation for 6 of the 52 variables assessed; however, all physiological values remained within clinically acceptable limits. No cardiovascular effects were noted. This study demonstrated that exposure to 1 percent Halon 1301 for 24 hr can produce minor disturbance of central nervous system function as assessed by cognitive tasks.
Document ID
19930055707
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
External Source(s)
Authors
Calkins, D. S.
(NASA Lyndon B. Johnson Space Center Houston, TX, United States)
Degioanni, J. J.
(NASA Lyndon B. Johnson Space Center Houston, TX, United States)
Tan, M. N.
(NASA Lyndon B. Johnson Space Center Houston, TX, United States)
Davis, J. R.
(NASA Lyndon B. Johnson Space Center Houston, TX, United States)
Pierson, D. L.
(Krug Life Sciences; NASA, Johnson Space Center Houston, TX, United States)
Date Acquired
August 16, 2013
Publication Date
February 1, 1993
Publication Information
Publication: Fundamental and Applied Toxicology
Volume: 20
Issue: 2
ISSN: 0272-0590
Subject Category
Aerospace Medicine
Accession Number
93A39704
Distribution Limits
Public
Copyright
Other

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