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Phenytoin as a countermeasure for motion sickness in NASA maritime operationsSeasickness is the most prevalent form of motion sickness and is an operational problem during Space Shuttle Solid-fueled Rocket Booster (SRB) retrieval. Phenytoin has been shown to protect against motion sickness induced by Coriolis stress. We exposed SRB recovery personnel to off-vertical rotation and sea motion after phenytoin or placebo. Phenytoin blood levels of at least 9 micrograms/ml were protective against motion sickness at sea. No change in susceptibility to nitrogen narcosis was seen in divers in chamber tests at 460 KPa. Phenytoin was used during the performance of critical and hazardous tasks during training and actual SRB recovery operations. Phenytoin is an effective operational countermeasure for motion sickness for selected SRB crew members.
Document ID
19930071165
Document Type
Reprint (Version printed in journal)
Authors
Woodard, Daniel (NASA John F. Kennedy Space Center Cocoa Beach, FL, United States)
Knox, Glenn (NASA John F. Kennedy Space Center Cocoa Beach, FL, United States)
Myers, K. J. (NASA John F. Kennedy Space Center Cocoa Beach, FL, United States)
Chelen, William (NASA John F. Kennedy Space Center Cocoa Beach, FL, United States)
Ferguson, Becki (NASA Kennedy Space Center Cocoa Beach; Florida Univ., Jacksonville, United States)
Date Acquired
August 16, 2013
Publication Date
May 1, 1993
Publication Information
Publication: Aviation, Space, and Environmental Medicine
Volume: 64
Issue: 5
ISSN: 0095-6562
Subject Category
AEROSPACE MEDICINE
Distribution Limits
Public
Copyright
Other