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Physics, chemistry and pulmonary sequelae of thermodegradation events in long-mission space flightAn event in which electronic insulation consisting of polytetrafluoroethylene undergoes thermodegradation on the Space Station Freedom is considered experimentally and theoretically from the initial chemistry and convective transport through pulmonary deposition in humans. The low-gravity enviroment impacts various stages of event simulation. Vapor-phase and particulate thermodegradation products were considered as potential spacecraft contaminants. A potential pathway for the production of ultrafine particles was identified. Different approaches to the simulation and prediction of contaminant transport were studied and used to predict the distribution of generic vapor-phase products in a Space Station model. A lung transport model was used to assess the pulmonary distribution of inhaled particles, and, finally, the impact of adaptation to low gravity on the human response to this inhalation risk was explored on the basis of known physiological modifications of the immune, endocrine, musculoskeletal and pulmonary systems that accompany space flight.
Document ID
19950058784
Acquisition Source
Legacy CDMS
Document Type
Conference Paper
Authors
Todd, Paul
(University of Colorado United States)
Sklar, Michael
(University of Colorado United States)
Ramirez, W. Fred
(University of Colorado United States)
Smith, Gerald J.
(University of Colorado United States)
Morgenthaler, George W.
(University of Colorado United States)
Oberdoerster, Guenter
(University of Rochester School of Medicine & Dentistry United States)
Date Acquired
August 16, 2013
Publication Date
January 1, 1993
Publication Information
ISSN: 0148-7191
Subject Category
Aerospace Medicine
Report/Patent Number
SAE PAPER 932144
Meeting Information
Meeting: International Conference on Environmental Systems
Location: Colorado Springs, CO
Country: United States
Start Date: July 12, 1993
End Date: July 15, 1993
Accession Number
95A90383
Distribution Limits
Public
Copyright
Other

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