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Cultivating Insect Cells To Produce Recombinant ProteinsMethod of producing recombinant proteins involves growth of insect cells in nutrient solution in cylindrical bioreactor rotating about cylindrical axis, oriented horizontally and infecting cells with viruses into which genes of selected type cloned. Genes in question those encoding production of desired proteins. Horizontal rotating bioreactor preferred for use in method, denoted by acronym "HARV", described in "High-Aspect-Ratio Rotating Cell-Culture Vessel" (MSC-21662).
Document ID
Document Type
Other - NASA Tech Brief
Spaulding, Glenn
(NASA Lyndon B. Johnson Space Center, Houston, TX.)
Goodwin, Thomas
(KRUG Life Sciences)
Prewett, Tacey
(KRUG Life Sciences)
Andrews, Angela
(Tulane Univ.)
Francis, Karen
(Tulane Univ.)
O'Connor, Kim
(Tulane Univ.)
Date Acquired
August 17, 2013
Publication Date
February 1, 1996
Publication Information
Publication: NASA Tech Briefs
Volume: 20
Issue: 2
ISSN: 0145-319X
Subject Category
Life Sciences
Report/Patent Number
Accession Number
Distribution Limits
Work of the US Gov. Public Use Permitted.

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