Cultivating Insect Cells To Produce Recombinant ProteinsMethod of producing recombinant proteins involves growth of insect cells in nutrient solution in cylindrical bioreactor rotating about cylindrical axis, oriented horizontally and infecting cells with viruses into which genes of selected type cloned. Genes in question those encoding production of desired proteins. Horizontal rotating bioreactor preferred for use in method, denoted by acronym "HARV", described in "High-Aspect-Ratio Rotating Cell-Culture Vessel" (MSC-21662).
Other - NASA Tech Brief
Spaulding, Glenn (NASA Lyndon B. Johnson Space Center, Houston, TX.)