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On the rat model of human osteopenias and osteoporosesThe idea that rats cannot model human osteopenias errs. The same mechanisms control gains in bone mass (longitudinal bone growth and modeling drifts) and losses (BMU-based remodeling), in young and aged rats and humans. Furthermore, they respond similarly in rats and man to mechanical influences, hormones, drugs and other agents.
Document ID
19970003763
Acquisition Source
Ames Research Center
Document Type
Reprint (Version printed in journal)
External Source(s)
doi:10.1016/0169-6009(92)90809-R
Authors
Frost, Harold M. (Southern Colorado Clinic Pueblo, CO United States)
Jee, Webster S. S. (Utah Univ. Salt Lake City, UT United States)
Date Acquired
August 17, 2013
Publication Date
January 1, 1992
Publication Information
Publication: Bone and Mineral
Publisher: Elsevier Science Publishers Ltd.
Volume: 18
ISSN: 0169-6009
Subject Category
Life Sciences (General)
Report/Patent Number
BAM-00464
NASA-CR-202679
NAS 1.26:202679
Accession Number
97N70240
Funding Number(s)
CONTRACT_GRANT: NAG2-435
CONTRACT_GRANT: DE-AC02-76EV-00119
CONTRACT_GRANT: DE-AF02-89ER-60764
CONTRACT_GRANT: NIH-AR-38346
Distribution Limits
Public
Copyright
Public Use Permitted.
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