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Record 37 of 273
On the rat model of human osteopenias and osteoporoses
Availability: Go to Request Form
External Online Source: doi:10.1016/0169-6009(92)90809-R
Author and Affiliation:
Frost, Harold M.(Southern Colorado Clinic, Dept. of Orthopaedic Surgery, Pueblo, CO United States)
Jee, Webster S. S.(Utah Univ., Radiobiology Div., Salt Lake City, UT United States)
Abstract: The idea that rats cannot model human osteopenias errs. The same mechanisms control gains in bone mass (longitudinal bone growth and modeling drifts) and losses (BMU-based remodeling), in young and aged rats and humans. Furthermore, they respond similarly in rats and man to mechanical influences, hormones, drugs and other agents.
Publication Date: Jan 01, 1992
Document ID:
19970003763
(Acquired Jan 30, 1997)
Accession Number: 97N70240
Subject Category: LIFE SCIENCES (GENERAL)
Report/Patent Number: NASA-CR-202679, NAS 1.26:202679, BAM-00464
Document Type: Reprint
Publication Information: Bone and Mineral; p. 227-236; (ISSN 0169-6009); Volume 18
Publisher Information: Elsevier Science Publishers Ltd., Barking, United Kingdom
Contract/Grant/Task Num: DE-AF02-89ER-60764; DE-AC02-76EV-00119; NAG2-435; NIH-AR-38346
Financial Sponsor: NASA Ames Research Center; ,Moffett Field,CA United States
Department of Energy; Washington, DC United States
National Inst. of Health; Bethesda, MD United States
Organization Source: Southern Colorado Clinic; Dept. of Orthopaedic Surgery; Pueblo, CO United States
Description: 10p; In English
Distribution Limits: Unclassified; Publicly available; Unlimited
Rights: Copyright; Distribution as joint owner in the copyright
NASA Terms: BONES; TISSUES (BIOLOGY); MASS DISTRIBUTION; HUMAN BODY; RATS; MUSCULOSKELETAL SYSTEM; COMPARISON; MODELS
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