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High-Moisture Diet for Laboratory Rats: Complete Blood Counts, Serum Biochemical Values, and Intestinal Enzyme ActivityRats were fed an irradiated high-moisture diet (KSC-25) with or without access to a water bottle. Physiologic values were compared between these two groups and a group of rats fed a purified diet. Hematologic and serum biochemical values, urine specific gravity, and intestinal enzyme activities were determined from samples collected from the three groups of rats. Sprague Dawley rats (n=32) fed the irradiated high-moisture diet with or without a water bottle were the test animals. Rats (n=16) fed an irradiated purified diet and water provided via a water bottle were the control group. The purified diet formulation, modified AIN-76A, is a commonly used purified diet for laboratory rodents. All rats remained alert and healthy throughout the study. A comparison of the physiologic values of rats in this study with reported normal values indicated that all of the rats in the study were in good health. Significant differences (P less than 0.05) of the physiologic values from each rat group are reported.
Document ID
19970012368
Acquisition Source
Kennedy Space Center
Document Type
Reprint (Version printed in journal)
Authors
Battles, August H.
(Bionetics Corp. Cocoa Beach, FL United States)
Knapka, Joseph T.
(National Inst. of Health Bethesda, MD United States)
Stevens, Bruce R.
(Florida Univ. Gainesville, FL United States)
Lewis, Laura
(Bionetics Corp. Cocoa Beach, FL United States)
Lang, Marie T.
(Bionetics Corp. Cocoa Beach, FL United States)
Gruendel, Douglas J.
(Bionetics Corp. Cocoa Beach, FL United States)
Date Acquired
August 17, 2013
Publication Date
June 1, 1991
Publication Information
Publication: Laboratory Animal Science
Volume: 41
Issue: 3
Subject Category
Life Sciences (General)
Report/Patent Number
NASA-TM-112287
NAS 1.15:112287
Accession Number
97N70960
Distribution Limits
Public
Copyright
Public Use Permitted.
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