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Physiology of Fluid and Electrolyte Responses During Inactivity: Water Immersion and Bed RestThis manuscript emphasizes the physiology of fluid-electrolyte-hormonal responses during the prolonged inactivity of bed rest and water immersion. An understanding of the total mechanism of adaptation (deconditioning) should provide more insight into the conditioning process. Findings that need to be confirmed during bed rest and immersion are: (1) the volume and tissues of origin of fluid shifted to the thorax and head; (2) interstitial fluid pressure changes in muscle and subcutaneous tissue, particularly during immersion; and (3) the composition of the incoming presumably interstitial fluid that contributes to the early hypervolemia. Better resolution of the time course and source of the diuretic fluid is needed. Important data will be forthcoming when hypotheses are tested involving the probable action of the emerging diuretic and natriuretic hormones, between themselves and among vasopressin and aldosterone, on diuresis and blood pressure control.
Document ID
19980008374
Acquisition Source
Ames Research Center
Document Type
Technical Memorandum (TM)
Authors
Greenleaf, John E.
(NASA Ames Research Center Moffett Field, CA United States)
Date Acquired
September 6, 2013
Publication Date
January 1, 1984
Publication Information
Publication: Medicine and Science in Sports and Exercise
Volume: 16
Issue: 1
Subject Category
Aerospace Medicine
Report/Patent Number
NASA-TM-112446
NAS 1.15:112446
Distribution Limits
Public
Copyright
Work of the US Gov. Public Use Permitted.
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