Abnormal Canine Bone Development Associated with Hypergravity ExposureChronic centrifugation of 85- to 92-day-old Beagles at 2.0 x g and 2.6 x g for 26 weeks during the time of active skeletal growth caused skeletal abnormalities in the radius and the ulna of ten of 11 dogs. The pattern of change mimicked that found in naturally occurring and experimentally induced premature distal ulnar physeal closure or delayed growth at this physis. Minimal changes in bone density were detected by sensitive photon absorptiometric techniques. Skeletal abnormalities also were found in five of the six cage-control dogs, although the run-control dogs were radiographically normal.
Document ID
19990041091
Acquisition Source
Ames Research Center
Document Type
Other
Authors
Morgan, J. P. (California Univ. Davis, CA United States)
Fisher, G. L. (California Univ. Davis, CA United States)
McNeill, K. L. (California Univ. Davis, CA United States)
Oyama, J. (NASA Ames Research Center Moffett Field, CA United States)
Date Acquired
August 19, 2013
Publication Date
January 1, 1979
Publication Information
Publication: American Journal of Veterinary Research