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Effects of Promethazine on Performance During Simulated Shuttle LandingsPromethazine (PMZ) is the antimotion sickness drug of choice in the U.S. Space Shuttle program; however, virtually nothing is known about the bioavailability and performance effects of this drug in the microgravity environment. PMZ has detrimental side effects on human performance on Earth that could affect Shuttle operations. In a recent ground-based study we examined: 1) the effects of promethazine (PMZ) on Shuttle landing performance using the portable inflight landing operations trainer (PILOT), and 2) saliva and urine samples to determine the pharmacokinetics of PMZ. The PILOT performance data is presented here.
Document ID
20000020506
Acquisition Source
Johnson Space Center
Document Type
Conference Paper
Authors
Harm, D. L. (NASA Johnson Space Center Houston, TX United States)
Putcha, L. (NASA Johnson Space Center Houston, TX United States)
Sekula, B. K. (Enterprise Advisory Services, Inc. Houston, TX United States)
Berens, K. L. (Wyle Labs., Inc. Houston, TX United States)
Date Acquired
August 19, 2013
Publication Date
January 1, 1999
Publication Information
Publication: Proceedings of the First Biennial Space Biomedical Investigators' Workshop
Subject Category
Aerospace Medicine
Distribution Limits
Public
Copyright
Work of the US Gov. Public Use Permitted.
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IDRelationTitle20000020485Collected WorksProceedings of the First Biennial Space Biomedical Investigators' Workshop
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