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Bone Density and High Salt Diets in a Space Flight ModelHigh salt diets accelerate bone loss with aging in patients with postmenopausal osteoporosis except when calcium supplementation is provided. We have observed that the decrease in mineral content of growing femurs in juvenile rats, exposed to a space flight model which unloads the hind limbs , is substantially less in animals fed excess salt. To determine whether excess dietary salt has the same effect on the skeleton of the mature animal whose response to unloading is increased resorption and bone loss rather than impaired growth, we carried out a metabolic study in mature rats with hindlimbs unloaded by tailsuspension.
Document ID
20000020519
Acquisition Source
Ames Research Center
Document Type
Conference Paper
Authors
Arnaud, S. B.
(NASA Ames Research Center Moffett Field, CA United States)
Navidi, M.
(Lockheed Martin Engineering and Science Services United States)
Liang, M. T. C.
(Bowling Green State Univ. OH United States)
Wolinsky, I.
(Houston Univ. TX United States)
Date Acquired
August 19, 2013
Publication Date
January 1, 1999
Publication Information
Publication: Proceedings of the First Biennial Space Biomedical Investigators' Workshop
Subject Category
Aerospace Medicine
Distribution Limits
Public
Copyright
Work of the US Gov. Public Use Permitted.
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